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OCR: ecretion Isolated disorders of pituitary hormone ons of can occur in the absence of structural les us, GH, or either the hypothalamus or pituitary. Th ted LH and FSH deficiency, can occur as isol isolated phenomena. These disorders result fron on: GH defects in hypothalamic hormone secret lof deficiency is due to a congenital deficien s from GHRH; and LH andFSH deficiency resul one deficient gonadotrophin-releasing horm (GnRH) secretion (Kallmann' syndrome ir less Isolated TSH and ACTH deficiencies occ d with commonly and are presumably associate e (TRH) ordeficient thyrotrophin-releasing hormo secretion, corticotrophin-releasing hormone (CRH respectively.